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Mechanisms of Action in GLP-1 Peptides GLP-1 peptides influence blood glucose, appetite, and energy balance by activating receptors in multiple organs

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Long-term administration of (Pro 3 )GIP to obese mice on an HFD was found to reduce body weight by about 8% compared to controls, without affecting food intake, and decrease casual blood glucose levels during the course of treatment and attenuated insulin levels during an oral glucose tolerance test [118]