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2009 Nov 24;54(22):210228

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doi: 10.1007/s00125-009-1515-4 92 CaoCYangSZhouZ

Our findings highlight that semaglutide not only improves cardiac structure and function but also exerts protective effects on intestinal integrity, supporting the existence of a gut metabolic heart axis in diet-induced obesity

Treatment with GLP-1RAs can regulate several pivotal miRNAs (such as miR-93-5p, miR-181a-5p and miR-34a-5p and miR-26a-5p) to inhibit apoptosis in endothelium [116]
