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These changes happen beyond what weight loss alone would provide

Nevertheless, there is a higher risk of hypoglycemia than with single GLP- 1 treatment

The question is what else is going with it

Learn how a board-certified Miami weight loss doctor can personalize your journey with GLP-1 and tirzepatide treatments

The SURMOUNT-5 trial (published in NEJM, 2025) demonstrated mean weight loss of 20.2% with tirzepatide versus 13.7% with semaglutide over 72 weeks in adults with obesity but without diabetes [10]
