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The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide

As much as 20% of people taking Ozempic for Type 2 diabetes reported nausea during clinical trials

In the 24-week, placebo-controlled factorial trial of initial therapy with sitagliptin in combination with metformin, the incidence of hypoglycemia was 0.6% in patients given placebo, 0.6% in patients given sitagliptin alone, 0.8% in patients given metformin alone, and 1.6% in patients given sitagliptin in combination with metformin

SGLT2 inhibitors is the ability of these medications to enhance the activity of incretin hormones (that is, GLP-1 and glucose-dependent insulinotropic polypeptide), delaying gastric emptying and reducing gastrointestinal motility, Alkabbani and colleagues explained

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