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Description
Because retatrutide combines all three mechanisms in one molecule, its trials have so far reported a larger average weight-loss effect than mazdutides, though the two have never been tested against each other directly, so that comparison is drawn across separate trials rather than a single head-to-head study

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Andersen A, Knop FK, Vilsbll T

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Anti-obesity pharmacological agents for polycystic ovary syndrome: a systematic review and meta-analysis to inform the 2023 international evidence-based guideline
