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In terms of weight loss outcomes, the injection delivers an average body weight reduction of around 15% at the maintenance dose, compared to approximately 16.6% with the tablet over a similar timeframe

The 2024 Yang paper in Journal for ImmunoTherapy of Cancer documented NNMT in cancer-associated fibroblasts driving tumour progression (PMID 39067875)

FIGURE 1 3.3 Signal values associated with different GLP-1 RAs We identified signals of AP events associated with all GLP-1 RAs using the criteria established by the four algorithms, and the results are summarized in Table 3

To me, durability is still the biggest unanswered question which could ultimately drive patient uptake across a somewhat competitive psychedelic drug class

The strength of association was presented as a mean difference and 95% confidence interval (CI)