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This review summarizes comparative evidence for providers who are determining which of the two classes may be the most appropriate for a specific patient
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Sources:TRIUMPH-1 (Lilly topline, May 2026), SURMOUNT-1 (Jastreboff NEJM 2022, DXA: Tobias DOM 2025), STEP 1 (Wilding NEJM 2021, DXA exploratory), ATTAIN-1 (Lilly/NEJM 2025), Phase 2 T2D DXA (Coskun, Lancet Diab Endo 2025)