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In particular, the aromatization of circulating androgens to estrone in adipose tissue depots amplifies the deregulation of gonadotropin secretion with worsening of hyperandrogenism

Few of these changes have had any noticeable impact on responses

Reitano said he expects that over the next two years, patients will bounce around among treatments as more options emerge

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Customization is an appropriate approach for patients who are seeking personalized medical attention, as it enables adjustments in dosage and delivery