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Description
Retatrutide is an investigational injectable medicine currently undergoing clinical evaluation for the treatment of obesity and type 2 diabetes
Using the GLP-QR agonist Exendin-4 (Exn-4) increased firing rates in arcuate nucleus (ARC) GLP-1R and POMC neurons, and the chemogenetic activation of ARC GLP-1R neurons significantly reduced food intake [132]
on the other hand, the comparison with insulin degludec showed that although insulin, titrated during the study, obtained a better result on fasting blood glucose, treatment with tirzepatide 10 and 15 mg demonstrated better control on all other points of glucose profile [60]
Get ready to learn how Retatrutide could turn your understanding of weight management upside down
doi: 10.1007/s13300-020-00981-0
