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Comparative evaluations explore whether triple agonism confers additive or synergistic benefits relative to single or dualagonist approaches

In the United States, the Centers for Disease Control and Prevention (CDC) reports that over 38.4 million individuals, approximately 11.6% of the population, are currently living with diabetes [2]

This review synthesizes evidence from over 15 peer-reviewed publications (20202026), prioritizing systematic reviews, meta-analyses, and phase 3/4 clinical trials extracted from PubMed

Wegovy (semaglutide) is specifically approved for chronic weight management in adults with obesity or overweight conditions