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Hypoglycemia risk is generally low when Zepbound is used as monotherapy for weight management, but increases substantially when combined with insulin or sulfonylureas in patients with diabetes
Il primo il confounding by indication : i pazienti trattati con semaglutide per il diabete tendono ad avere una malattia di maggiore durata e complessit rispetto ai controlli non trattati, con un profilo di rischio microvascolare intrinsecamente pi elevato (vedi la sezione: Sicurezza dei farmaci)
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