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Notes : a Obesity, body mass index (BMI) of 30 kg/m 2 or greater

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For patients new to exercise, gradual progression is essential

however, PTX reversed the constitutive inhibition of forskolin-stimulated cAMP associated with hGPR17L expression (Figure 2A), suggesting that constitutive inhibition of cAMP by hGPR17L is mediated by Gi/o signaling

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