glp-1 agonists herbs Do Patches Really Work? Evidence and FDA-Approved Alternatives Herbal Medicines in the Management

Montanya E, Sesti G

Building on the therapeutic success of GLP-1RAs, recent pharmacological developments have introduced GLP-1 with glucose-dependent insulinotropic polypeptide (GIP)/glucagon (GCG) dual or triple receptor agonists simultaneously target multiple incretin pathways, offering a novel multi-targeted approach to MASLD treatment

reported greater weight loss in obese mice with the GLP-1/GIP/glucagon receptor triagonist compared to GLP-1 receptor agonists, GIP/GLP-1 receptor co-agonists and GLP-1/glucagon receptor agonists including semaglutide and tirzepatide [60]

This can potentially reduce post-meal glucose levels Suppress your appetite and improve satiety Suppresses the release of glucagon, which can help reduce excess glucose production by the liver

GLP-1RAs prevent post-MI remodeling by having an impact on the extracellular matrix changes rather than dependency on its glycemic control [76]