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(21) In the context of significant weight loss, reduced skeletal loading may lead to an imbalance favoring osteoclastic activity and bone resorption, which could explain the decreased BMD observed in semaglutide-treated patients

J Lipid Res 52 , 7886 (2011)

Dietary Supplements

Eating smaller, frequent meals and avoiding high-fat foods can help manage symptoms during this adjustment period

AOMs, including GLP-1s, may help regulate appetite and eating behaviors, though certain AOMs can exacerbate obesity-related conditions and should be carefully monitored
