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Since PF-06882961 does not activate the rodent GLP-1R, the therapeutic effects of PF-06882961 on insulin and glucose were examined in an IV glucose tolerance test (IVGTT) in cynomolgus monkeys

Researchers believe that nausea/vomiting is related to greater weight loss (90)

Rodriguez, K

Theres nothing negative about it, I just dont like taking medicine. Right now, shes still taking the drug, but is working with her providers to determine the best way to discontinue it once shes reached her goal, which is her prerogative

Together, these findings support the hypothesis that decreased endogenous GLP-1 signaling promotes/facilitates drug seeking and that activating central GLP-1-producing neural circuits may attenuate cocaine-seeking behavior during abstinence