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The combination may significantly amplify these symptoms, potentially leading to dehydration, electrolyte imbalances, and reduced medication adherence

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The outcome measures of interest include average drinks (Poisson distribution) and binge drinking (Binomial distribution) calculated from TLFB, AUDIT scores (Gaussian distribution), alcohol use per episode of use (Gaussian distribution) and the sedative and stimulative scores from the BAES scale (Gaussian distribution)

Cox proportional hazards models : Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals for the association between study group and time to outcome

Translational Research, 205 , 5163