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Description
Gastrointestinal side effects: GLP-1-based agents, including retatrutide, commonly cause nausea, vomiting, diarrhoea, and reduced appetite, partly through slowing of gastric emptying
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Constipation Constipation may be from reduced food intake or change in diet as well as slower gut motility
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Metformin alleviates inflammation through suppressing FASN-dependent palmitoylation of Akt
