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There are still significant knowledge gaps regarding the long-term GI safety of GLP-1-based therapies and the optimal management of persistent or delayed-onset symptoms

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First, the small sample size was secondary to: (a) a national shortage of GLP-1 receptor agonists during the study period [32] with pharmacy availability issues

If you have diabetes and take insulin or sulfonylureas, work with your healthcare provider to adjust medication timing and dosing to prevent hypoglycemia
