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Description
The overlapping receptor activation creates unpredictable effects and dramatically increases GI side effect risk
While compounded medications are not FDA-approved, they can be a personalized option for those looking for specific preparations or navigating supply issues
Furthermore, concentrations of up to 300 mM glucose do not induce GLP-1 secretion from colonic human mucosa because GLP-1 producing L-cells barely express SGLT1 (43, 53, 58, 72)
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Diabetes Obes Metab 2025
