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In contrast, early randomized controlled trials in humans did not demonstrate a clear increase in malignancy rates, yet those trials were not powered to detect rare cancer outcomes

Note: GLP-1 brands include Victoza, Trulicity, Saxenda, Ozempic, Rybelsus, Wegovy, and Mounjaro

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This can cause the effect of compounded semaglutide (Ozempic and Wegovy) or compounded tirzepatide (Zepbound and Mounjaro) to become less pronounced, leading to a weight loss plateau

Obesity, we can all agree, is a vitally important issue underpinning many causes of mobility and mortality