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The landmark SURMOUNT-1 trial demonstrated average weight loss of approximately 20% of body weight over 72 weeks at the highest dose greater than any single-receptor GLP-1 drug

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Aggregated peptide is not just less effective

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Research Applications GIP/GLP-1 receptor binding and selectivity: Characterization of dual agonist binding affinities , receptor occupancy , and structureactivity relationships for GIP versus GLP-1 receptors

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