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The therapy was also generally well tolerated, with mostly mild injection-site reactions and no increased risk of serious infections, thrombosis, or cardiovascular events

Over the next 10 months in clinic, his GDMT was titrated to carvedilol 25mg BID, spironolactone 25mg daily and Sacubitril/Valsartan 49-51mg BID

Leptin is produced by fat cells, and whats ironic is those who have difficulty losing weight generally have leptin resistance

We've been using them safely in medicine for decades nicotine replacement, hormone replacement therapy (HRT), some pain medications, motion sickness drugs, certain heart treatments