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There are several unknown reasons why the pancreas is unable to produce enough insulin for the body when it is diagnosed with type 2 diabetes

Endocrinology (United States) 156(10):35593569

Interestingly, GLP-1RA antidiabetic drugs have shown a distinct effect in reducing the incidence of stroke and enhancing neuroprotection in both pre-clinical and clinical studies (80, 81)

This means it works by mimicking the action of two important hormones involved in blood sugar regulation

A meta-analysis across multiple studies confirmed the pattern: tirzepatide produces roughly 4.23 kg (about 9.3 pounds) more weight loss than semaglutide on average