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Description
7 At the time of the SURPASS2 study design and conduct, 1 mg was the highest approved dose of semaglutide for the management of patients with T2D who had shown superiority in lowering glucose levels and reducing body weight compared with two selective GLP1 RAs, dulaglutide (0.75 and 1.5 mg) and exenatide (2 mg) once weekly, with a similar safety profile
Do not redial the dose
This start-low,-go-slow approach balances efficacy with minimised GI side effects and improves adherence during the transition period
This prevents confusion and ensures you use the oldest vials first
It can help people feel full sooner and reduce hunger between meals
