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Description
Retatrutide is the first medication to mimic three hormones, GLP-1, GIP and glucagon, rather than the one or two that current medications use
PMID: 15087503
[2] Other GLP-1s have similar profiles
Tirzepatide targets both the GLP-1 and GIP receptors simultaneously, creating what researchers call a "twincretin" effect
This is a physiological effect of weight loss, not a direct drug interaction
