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These effects depend on the type, route of administration, dose, and duration of action of each specific GLP-1 receptor agonist, as well as individual characteristics such as baseline body weight and degree of glucose tolerance
Key Nutritional and Metabolic Risks Associated with GLP-1 Therapy Appetite Suppression and Reduced Nutrient Intake GLP-1s function by promoting satiety and delaying gastric emptying, often resulting in significant reductions in overall caloric and protein intake
doi: 10.1038/s41443-018-0054-2
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