evaluate novo nordisk on glp-1 agonists Understanding receptor and their impact drug discovery GLP-1 Market Industry Trends and

Alzheimers Dement (2022) 18:70089

Do you need a prescription for GLP-1 drugs

doi: 10.1002/msj.20159 [DOI] [PMC free article] [PubMed] [Google Scholar] 127

Michael Greger explores the science behind these medications and gives us the answers we need

(Right) GLP-1 receptor agonist (GLP-1RA) reduces cholesterol accumulation by affecting the expression of genes in the hepato-enteral circulation and cholesterol reverse transport pathway, such as farnesoid X receptor (FXR), fibroblast growth factor-15 (FGF15), fibroblast growth factor receptor 4 (FGFR4), cytochrome P450 family 7 subfamily A member 1 (Cyp7a1), proprotein convertase subtilisin/kexin type 9 (PCSK9), low-density lipoprotein receptor (LDLR), etc