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Conclusion In this NMA, tirzepatide 10 and 15 mg were associated with improved efficacy versus liraglutide, improved or comparable efficacy versus semaglutide, and all interventions had a generally comparable safety profile for achieving weight reduction and reducing cardiometabolic risk factors among patients with obesity or overweight.

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Weight loss drugs are more popular than ever, even in cycling, but do the health benefits some are seeing outweigh the risks and dangers, and what does WADA think of them?