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These lifestyle changes complement the effects of GLP-1 agonists, leading to better health outcomes and reducing the long-term risks associated with Type 2 diabetes and obesity

In a rat ischemia-reperfusion model using isolated perfused heart and whole animal, GLP-1 significantly decreased infarction size, and this protection was abolished by exendin 939 , as well as inhibitors of adenylyl cyclase, phosphatidylinositol 3-kinase (PI3K), and p42/44 mitogen-activated protein kinase (MAPK), suggesting that these pathways were involved in GLP-1mediated cardio-protection (Bose et al., 2005a)

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Slows Digestion Semaglutide also slows down the movement of food through the stomach and intestines

Hankosky, E.R