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Another GLP agonist, lixisenatide (which is not approved for obesity), improved motor function in early Parkinsons disease (Meissner WG et al, N Eng J Med 2024;390:11761185)

Suppressing glucagon (which raises blood sugar)

The growing popularity of Mounjaro, Zepbound (which also contains tirzepatide), and GLP-1 receptor agonists such as Ozempic and Wegovy has led to periodic shortages, making it difficult at times to find these medicines in pharmacies

This novel concept could explain why the GLP-1 analog might be superior to a DPP-4 inhibitor for the management of pasireotide-induced hyperglycemia

By Kamruz Darabi, MD, FAAD, FASMS Triple board-certified dermatologist, Mohs skin cancer surgeon, and dermatopathologist at Darabi Dermatology, serving Chaska, Hutchinson, and Shakopee, Minnesota