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The gutbrain axis enables bidirectional communication between the brain and the gastrointestinal system, involving neuroendocrine pathways, the vagus nerve, immune factors, and microbiota (Carabotti et al., 2015

Common Side Effects Nausea Diarrhea Vomiting Constipation Stomach Pain Decreased Appetite Headache Serious Side Effects (less common) Possible inflammation of the pancreas (pancreatitis) Gallbladder issues Kidney problemsoften linked to dehydration caused by symptoms like nausea or vomiting Serious allergic reactions Vision alterations, particularly in patients with type 2 diabetes Increased heart rate Notably, oral semaglutide includes a boxed warning related to risks of thyroid C-cell tumors, although these findings were primarily based on animal studies

By slowing digestion, reducing hunger, and increasing feelings of fullness, semaglutide makes it easier to eat less without feeling deprived

Even though obesity affects about 14 percent of the French population, the drug will only be available under a restricted framework by French medicine safety watchdog the Agence Nationale de Scurit du Mdicament (ANSM)

Meanwhile, a concerning trend also has emerged on TikTok where users promote taking laxatives, particularly Miralax, on a daily basis, with the hashtag #GutTok racking up over 1.1 billion views