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The atherosclerotic benefits provided by GLP-1RA, which reflect the improvement of glycated hemoglobin level, blood pressure, albumin-to-creatinine ratio and other favorable hemodynamic effects, may be responsible, at least in part, for this finding

Body-Mass Index Evolution of BMI over time

[DOI] [PMC free article] [PubMed] [Google Scholar] 293.Papathanasiou T., Strathe A., Agers H., Lund T.M., Overgaard R.V

These duration and agent dependent associations are consistent with potential disease modifying activity beyond weight loss alone, although prospective trials are needed to establish causality and define optimal treatment targets." Commenting on the research, Professor Lucy Donaldson, director of research at Arthritis UK, described the study as "encouraging." She stated: "This is an encouraging study which suggests that people with knee osteoarthritis who were taking weight loss medications were less likely to need knee replacement surgery compared to those not taking these medicines

Do GLP-1 medicines increase heart rate