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Certain blood pressure medications, including ACE inhibitors and some beta-blockers, may have enhanced effects when paired with semaglutide due to changes in kidney function or fluid balance

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Maciejewski ML, Arterburn DE, Van Scoyoc L, et al

Doctors usually start at a low dose and increase it slowly

and from 1.10 to 1.22 G, E rev =100.5 mV, green dots in Fig