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Journal of the Endocrine Society , 5(Suppl 1)

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[1] [2] There is no official recommendation favoring morning versus evening administration, as the pharmacokinetic profile of tirzepatidewith its extended half-life and once-weekly dosingmaintains stable therapeutic levels regardless of injection time

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9 In this review, we systematically examine current evidence on the multifaceted mechanisms, clinical consequences, and potential intervention strategies related to weight lossinduced bone loss

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