orforglipron vs semaglutide New GLP pill, orforglipron, versus established GLP pill, in those with obesity & type 2 diabetes. 1️⃣Average blood sugar improved slightly more with (reduced HbA1c by 2.2% from baseline 8.3%) Orforglipron, an Oral Small-Molecule GLP-1

9 There is a lack of direct evidence, highlighting the need for further research to deepen our understanding of the association between semaglutide and alopecia areata

Published 2024 Jan 29

GLP-1/GCG protein, Human (HEK293, His), is a recombinant GLP-1/GCG protein expressed by HEK293 cells, with a His tag at the C-terminus, and is composed of 160 amino acids (R21-K180)

T2DM predisposes patients to diabetic cardiomyopathy and atherosclerotic cardiovascular disease, which can often result in heart failure through a variety of mechanisms, including myocardial infarction and chronic pressure overload [2]

Its stimulant properties increase heart rate and blood pressure, making it unsuitable for individuals with cardiovascular risk factors