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As humans do not produce TMCA, we then examined the relationship between the levels of fecal non-12-OH FXR-antagonistic BA species (HDCA and UDCA-related species) and the levels of serum T3 in the same cohort

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Interestingly, it is the result of the dysbiosis itself instead of the NLRP6-deficiency, as it could be transferred in wild-type mice

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