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For reasons that still aren't understood, the same drug works far better for some people than for others

Patients with personal history of colon cancer can generally receive GLP-1 agonists if otherwise appropriate, as no evidence suggests these drugs increase recurrence risk

The bottom line Nausea is a common side effect when taking a GLP-1 because of the way the medication slows down digestion

Mounjaro and Zepbound have positioned Lilly as a commercial force, while retatrutide and orforglipron give the company strong next-generation optionality

BMI 35 to 40 (class 2 obesity) People starting with class 2 obesity often experience the most significant health improvements