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Description
When considering GLP-1 agonists for any indication, clinicians and patients must be aware of the established side effect profile of these medications

The First Wave: Older GLP-1 Medications Before semaglutide stole the spotlight, several other GLP-1 agonists were used primarily for diabetes management, with modest weight loss benefits

GLP-1 RA use in complicated diabetes: There is no clear evidence regarding the use of GLP-1 RA in acute myocardial infarction, although the use of these agents is encouraged in patients with asymptomatic and stable coronary artery disease (CAD)

There are other mechanisms by which circulating incretin mimetics can influence deep brain function without crossing the blood-brain barrier
The individual properties of the various GLP-1 receptor agonists might enable incretin-based treatment of type 2 diabetes mellitus to be tailored to the needs of each patient
