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Studies in which histamine synthesis was chemically inactivated failed to observe the normal leptin-induced suppression of food intake and decrease in body weight (79, 80, 133)

You can read the abstract of this article at The idea of Reward Deficiency Syndrome suggests that addiction to various substances occurs because they stimulate the brains reward system so intensely that the population of dopamine D2 receptors (DD2R) decreases

4G,I) in Ghsr- and Glp1r- expressing NG neurons, respectively

10.1016/j.addr.2018.07.009 93 ZhangH.WuT.WuY.PengY.WeiX.LuT.et al (2024)

Sun, Y., Koyama, Y
