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Patients with certain genetic profiles may tolerate earlier injections better or benefit from evening dosing to spread side effects during sleep, optimizing comfort without changing your actual injection day

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This guidance comes from concerns about how it affects metabolism, potential risks to a developing baby from early studies, and the absence of well-controlled studies in pregnant humans

When food stays in the stomach longer, it can start to ferment and produce excess gas, including hydrogen sulfide, the gas that causes sulfur-smelling burps

Other socioeconomic factor may factor in to this, such as the high cost of GLP-1RAs (which can limit affordability for lower-income patients and those with Medicaid compared to private insurance coverage), formulary restrictions, provider-level prescribing bias, and patient-level preferences 16