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[40] evaluated the effects of liraglutide on cardiovascular risk biomarkers such as adiponectin, leptin, high-sensitivity C-reactive protein (hs-CRP), interleukin 6 (IL-6), tumor necrosis factor (TNF-), plasminogen activator inhibitor 1 (PAI-1), and B-type natriuretic peptide (BNP)

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These cells then enter the circulation and ultimately exert their effector functions within the CNS, crossing the BBB or the blood-cerebrospinal fluid (CSF) barrier at the choroid plexus [112]

When tirzepatide binds to cardiac GLP-1 receptors, it modulates vagal tone

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