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This can also lead to stimulation of the sympathetic nervous system and downregulation of parasympathetic tone via the vagus nerve through the dorsal motor nucleus of the vagus

With improved weight loss and the additional pleiotropic benefits of GIP, other metabolic risk factors are improved with tirzepatide

Due to the increasing epidemic boost of T2DM in recent years, whose trend will be confirmed in the next decades (3, 4), the need of reducing the CV risk in diabetic patients has become a priority

Chowdhury TA, Escudier V
