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Evidence also suggests antidepressant effects of GLP-1RAs

Most patients naturally eat smaller portions and feel more in control of cravings

All animals (up to 5 mice per cage) were housed under controlled conditions in ventilated cages, including a 12-h light/dark cycle, temperatures of 22 4 C or 21 2 C, and relative humidity ranges of 50 15% or 3070% at The Jackson Laboratory and Oslo University Hospital Rikshospitalet, respectively

Originally developed for type 2 diabetes, these therapies are now helping thousands achieve effective, doctor-supervised weight reduction

Clinical trials demonstrate that maximal therapeutic effects generally require several months of treatment at the target maintenance dose, which is typically reached through a gradual dose escalation process