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Using the same spot repeatedly can cause lipohypertrophy (hardened areas under the skin) that impair absorption

Pacing Clin Electrophysiol 2010;33:13921406

Many experts view these medications as long-term treatments for appropriate candidates rather than short-term interventions

But you do need a reality check especially if you've stalled

The mechanism involves glucose-dependent insulin secretion, meaning insulin release occurs primarily when blood glucose levels are elevated, thereby reducing the risk of hypoglycemia when used as monotherapy
