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15 Hormonal imbalances in PCOS affect cyclic endometrial cellular proliferation and tissue differentiation, resulting in immune and inflammatory dysregulation, as well as altered angiogenesis, which are the major pathology pathways contributing to endometrialfactor infertility in PCOS

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Additionally, using semaglutide has been shown to significantly improve insulin sensitivity and the ability of pancreatic beta-cells to produce and secrete insulin

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