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Recent evidence has demonstrated that GLP-1 receptors are expressed in the choroid plexus, suggesting a direct mechanism for modulating CSF dynamics independent of weight loss effects [6, 7]
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Maagensen, H., Larsen, J
Additionally, angiotensin II contributes to endothelial dysfunction by inducing expression of vascular endothelial growth factor and increasing reactive oxygen species, which reduce the bioavailability of vasodilators (such as nitrous oxide) responsible for maintaining normal glomerular vascular tone [14]
It should not be used for this purpose until there is sufficient evidence to support relevant guidelines
