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In SURMOUNT-1 , the pivotal Phase 3 trial in adults with obesity, average weight loss at the 15 mg dose was around 20% over 72 weeks

Clinical trial data from Eli Lilly shows that fatigue affects between 5% and 7% of people taking Zepbound, the weight loss formulation of tirzepatide
Mounjaro users typically lose 3-5 lbs in their first month, reach 15% body weight reduction by month 12, and can achieve up to 21% loss by week 72 -making it one of the fastest-acting GLP-1 weight loss medications available today

There is no established dose equivalence table between these compounds because they have different receptor profiles and potencies
