what is a compound glp 1 Managing Compounded GLP-1 Medications: Pharmacist's Guide for Employers – Sequoia Compounded GLP-1s: Why doctors worry
Description
doi: 10.1056/NEJMoa1306033
The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation
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As such, they have not historically been mass-produced, and they are not subject to the same approval processes as standard pharmaceutical drugs
Risk Stratification & Contraindications Patient safety must guide the initiation of GLP-1 therapy, and therapy should be withheld if contraindications are present: Absolute Contraindications: Personal or family history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Cautionary History: Previous pancreatitis or gastroparesis 5
doi: 10.1002/lim2.43
