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Metabolic and hormonal changes after laparoscopic roux-en-Y gastric bypass and sleeve gastrectomy: a randomized, prospective trial
Subsequent pooled analyses and randomized studies demonstrated that sustained aspirin use can reduce colorectal cancer incidence by approximately 2030%, with benefits emerging after five or more years of continuous exposure

2020 Nov 5;80(3):485-500

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Many semaglutide users find this provides consistent, gentle relief that keeps the colon moving and reduces bladder compression