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You might have heard of some of them, like semaglutide or liraglutide

Additionally, some users may unintentionally under-eat due to appetite suppression, leading to low caloric intake, dehydration, or even vitamin deficiencies

NICE guidance supports their use in type 2 diabetes for people with established cardiovascular disease or high cardiovascular risk, or when additional therapy is needed despite metformin and/or SGLT2 inhibitors

We gratefully acknowledge All of Us participants for their contributions, without whom this research would not have been possible